Wednesday Slide Conference, 2025-2026, Conference 9, Case 2
Signalment:
12-year-old neutered male Pomeranian dog (Canis lupus familiaris)History:
Gross Pathology:Four skin biopsy punches from the abdomen, thigh, neck, and chest were received and processed.
Laboratory Results:
N/AMicroscopic Description:
Haired skin. Alle the biopsies are histologically similar. The superficial and mid dermis is obscured by a moderate to severe inflammatory infiltrate, often obscuring the dermo-epidermal junction. The inflammatory infiltrate is represented by a prevalence of lymphocytes and plasma cells, macrophages occasionally engulfing melanin (melanophages), and rare neutrophils. The epidermis is moderately thickened (irregular hyperplasia), with mild intercellular edema (spongiosis) and severe thickening of the stratum corneum by predominantly nucleated (parakeratotic hyperkeratosis) or less frequently non-nucleated keratin (orthokeratotic hyperkeratosis). Numerous apoptotic figures are observed throughout the epidermis, occasionally surrounded by lymphocytic satellitosis. Similar lesions are observed in the hair follicles. There is multifocal erosion or ulceration of the epidermis; the ulcerated areas are obscured by serocellular crusts.Contributor's Morphologic Diagnoses:
MD: Haired skin. Lymphoplasmacytic interface dermatitis, diffuse moderate chronic, with epidermal hyperplasia, numerous suprabasal apoptosis with lymphocytic satellitosis, parakeratosisND: Hyperkeratotic erythema multiforme
Contributor's Comment:
TBDContributing Institution:
San Marco Veterinary Clinic and Laboratory, Pathology division, Viale dell'Industria 3, 35030, Veggiano (PD), Italy https://www.clinicaveterinariasanmarco.it/JPC Diagnoses:
TBDJPC Comment:
TBDReferences:
- TBD
